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Can metastasis be stopped? 

Find out if your dog qualifies for Tina's Trial: 

EGFR/HER2 Vaccine Study 

A new cancer immunotherapy developed by researchers at Yale U is being evaluated in this study led by Therajan LLC 


May 13, 2024

Webinar with Prof Mark Mamula


Apr 25, 2024

A new clinical trial site in Connecticut has been added.

To learn more, email Dr. Lindsay Thalheim's team at

Sign up for Wag Love Life Walk and 5K

May 5, 2024;  Virtual Participants Welcome!


Apr 2, 2024, 

Webinar: Hemangiosarcoma Research 


Mar 21-24, 2024

World Veterinary Cancer Congress: Poster Presentation - "Overall, one-year survival of osteosarcoma patients: 65%. Early studies indicate 70% of hemangiosarcoma patients are alive at 5 months post-splenectomy."


Feb 2, 2024

Northern Virginia MedVet clinic will be focusing on osteosarcoma patients.  They will not be enrolling patients with hemangiosarcoma or TCC. 


Jan 30, 2024  

Webinar:  The Promise of Immunotherapy Recording

What new treatment options are becoming available? How can I increase the chance of my dog responding to immunotherapy?

Jan 1

Love Calendar is available.  Suggested donation is $35. Please donate here to order. 

Dec 1, 2023
Tribute Tails Fundraiser remains open. Please support the study by launching your Tribute Tails Fundraiser ( friends & family fundraiser) in honor of your pup.  If you have already started a fundraiser or donated, a big thank you❤️️

July 6,  2023
An update on study requirements and vaccine availability.  Learn more   


Why immunotherapy?

  • May stop or slow the recurrence and spreading of cancer

  • May help when surgery is not possible, or if chemotherapy doesn't work

  • May slow or reverse cancer metastasis

Maggie 2023.jpg

Maggie was diagnosed with osteosarcoma in Jan 2020 and got conventional treatment plus the vaccine.  She is still cancer-free.


Ranger's cancer kept on spreading, even after surgery and chemotherapy.  But his tumors shrank and disappeared after the EGFR/HER2 vaccine treatment.


Codi's metastatic osteosarcoma began to disappear a month after he received the EGFR/HER2 vaccine injection. He enjoyed 3 extra years as a healthy, happy pup.

How does it work?

  • Safely activates the immune system against cancer cells that are over-expressing EGFR and HER2 proteins.

  • The vaccine has already been given to over 600 canine patients. Minimum side effects reported. 

  • May help with many different cancer types. Preliminary data for osteosarcoma and hemangiosarcoma published.  

  • Watch a recent update from the team.

Limitations and Challenges

  • Today's immunotherapy cannot guarantee every dog will become a long-term survivor. 

  • Researchers are investigating different ways to safely enhance the efficacy and increase the number of responders.

Learn about strategies that might enhance efficacy of immunotherapy treatments.

Please contact us at

with any questions.

New Study Locations

Clinical Trial Locations  L



Salt Lake City




















Dr Chelsea Tripp

Dr Rance Sellon

Dr Katie Wright

Dr Rochelle Prudic

Dr Christine Anderson

Dr Karina Valerius

Dr Betsy Hershey

Dr Roberta Portela

Dr Brendan Boostrom

Dr Melissa Miller

Dr. Lindsay Thalheim

(425) 697-2272

(509) 335-0711

(385) 341-4444

(216) 362-6000

(724) 717-2273

(513) 561-0069

(602) 841-0626

(773) 281-7110

(703) 361-8287

(804) 206-9122

Click here to open google map

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Stay Involved

How can I best help my pup respond to the vaccine?

Anything to avoid? Can dietary intervention help?

What's the relationship between cancer and gut microbiome?

Will checkpoint inhibitors become available?

How can I contribute my pup's samples to the study?

Receive email updates and invitation to future zoom sessions.

Please contact us at

with any questions.

Updates and Resources


  • Webinar and Q&A session on Jan 30. Watch here.

  • Prof. Mark Mamula will present recent research findings at the next World Veterinary Cancer Congress in Tokyo, Japan in March.

  • TheraJan is a newly formed company that will be commercializing the vaccine.  Please visit the TheraJan website for more information.

  • Tribute Tails Fundraiser open. We have exceeded the anticipated enrollment for the study and are running out of funds.  Please join the Tribute Tails ( friends & family fundraiser ) in honor of your pup so we can continue the study.  If you have already donated, a big thank you ❤️️

  • Aug 21, 2023 Two new locations in Ontario and Virginia have been added.  The study location in CA will be closing.

  • July 6, 2023 Because of the high demand for the vaccine, the research team has provided new study requirements and vaccine availability update which can be read here.

  • May 25, 2023  Many of the new clinics are creating wait lists.  Additional vaccine are being shipped to all the clinics.  

  • May 20, 2023 USDA approves eight additional clinical trial sites, making the total 10 study locations.

  • May 17, 2023 New locations will soon be announced. Please sign up if you'd like to receive an email notification of new study locations and other information about immunotherapy and research.

  • May 17, 2023 Washington State University WSU will be pausing radiation treatment from end of June until Sept as they update their linear accelerator.  If you live in the Pacific Northwest and are looking for vaccine + radiation therapy option, please consult your oncologist.  The veterinary hospital in Portland, Oregon is offering radiation therapy.  None of the clinics in Seattle offers radiation therapy.

  • May 3, 2023 Bridge Animal Referral Center BARC in Edmonds WA is continuing to enroll patients. Call for an appointment.  (It’s easiest and quickest to make an appointment if your dog is already seeing an oncologist because your dog just needs to come in for office visits for two vaccine shots plus a blood draw.     If you need to set up an appointment as a new oncology patient, the wait time may be 2-3 months.  By the way, there is no radiation treatment option at this clinic)

  • May 3,  2023 Washington State University Veterinary Hospital is accepting patients.  For dogs who are not candidates for surgery.  Radiation therapy + vaccine.

Other Resources


Papers and Presentations


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"Thank you for this incredible work, for the second chance for each dog to live a full life, joyful at the side of their humans. " - Sharon L.

This study is made possible by donations from loving pet parents ♥️

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