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Electrochemotherapy (ECT) for Dogs and Cats

A New Way to Treat Tumors - When Surgery Isn’t Enough

Electrochemotherapy (ECT) is helping dogs and cats with cancer-especially when tumors are difficult to remove, have come back, or aren’t responding well to standard treatments.


In this expert webinar, Dr. Chelsea Tripp explains how this minimally invasive therapy works, which tumors respond best, and how it can improve both survival and quality of life.


👉 If your dog or cat has a tumor that’s hard to remove or keeps coming back, this is a treatment worth understanding.


🎥 Watch the Webinar


Who Should Watch This Webinar?

• Pet owners of dogs or cats recently diagnosed with cancer

• Individuals exploring alternatives to surgery or radiation therapy

• Those interested in emerging or minimally invasive cancer treatments

• Veterinary professionals seeking to expand their knowledge of ECT


About the Webinar

This webinar provides an in-depth overview of electrochemotherapy, including its mechanism of action, clinical applications, and real-world case examples. Dr. Tripp shares insights from recent studies and clinical experience, demonstrating how ECT can be used for local tumor control while preserving function and quality of life.


How Electrochemotherapy Works

Electrochemotherapy utilizes a process called electroporation. Short, controlled electrical pulses temporarily open microscopic pores in the cell membrane, allowing chemotherapy drugs-such as bleomycin or cisplatin-to enter cancer cells at significantly higher concentrations. 


Once the pores close, the drugs are trapped inside the cells, enhancing their cytotoxic effect.

In addition to direct tumor cell destruction, ECT can disrupt the tumor’s blood supply and stimulate an immune response, thereby improving local tumor control and reducing chance of recurrence.


Key Takeaways

• ECT enhances the effectiveness of chemotherapy through electroporation, with very low-dose chemo.

• Commonly treated tumors include mast cell tumors, soft tissue sarcomas, squamous cell carcinomas, melanomas, and epulides.

• ECT has minimal systemic toxicity and minimal side effects.

• ECT can be more affordable than radiation therapy or chemotherapy.

• The therapy can be repeated if tumors recur and may serve as an alternative to radiation therapy in certain cases.


Tumors Commonly Treated with ECT

• Mast Cell Tumors

• Soft Tissue Sarcomas

• Squamous Cell Carcinoma

• Melanoma

• Acanthomatous Epulis

• Perianal and Rectal Tumors

• Cutaneous and Subcutaneous Hemangiosarcoma

• Superficial tumors in exotic species such as rabbits and birds


Benefits of Electrochemotherapy

• Minimally invasive with a short anesthesia time

• Outpatient procedure with rapid recovery

• Lower systemic chemotherapy exposure

• Effective local tumor control

• Ability to preserve anatomical structures and function

• Repeatable treatment option


Frequently Asked Questions (FAQ)

1. What are the benefits of ECT?

• Minimally invasive with a short anesthesia time

• Outpatient procedure with rapid recovery

• Lower systemic chemotherapy exposure

• Effective local tumor control

• Ability to preserve anatomical structures and function

• Repeatable treatment option


2 What are the tumors commonly treated with ECT?

• Mast Cell Tumors

• Soft Tissue Sarcomas

• Squamous Cell Carcinoma

• Melanoma

• Acanthomatous Epulis

• Perianal and Rectal Tumors

• Cutaneous and Subcutaneous Hemangiosarcoma

• Superficial tumors in exotic species such as rabbits and birds


3. Is electrochemotherapy safe?

Yes. Pets are under sedation or light anesthesia, so they are comfortable during the procedure. While the electrical pulses cause brief muscle contractions, the treatment itself is short and very well tolerated, with minimal side effects.


4. If surgery couldn’t remove all the cancer, how can ECT help?

ECT doesn’t just target the visible tumor - it can also help the body recognize what’s left behind. By damaging cancer cells in a way that exposes them to the immune system, ECT can trigger an immune response that helps attack remaining cancer cells after surgery.


5. How many treatments are needed?

Many patients only require only a single treatment.  Some patients benefit from multiple sessions.  


6. Why didn’t my vet mention this option?

Although electrochemotherapy has a long track record in Europe, it’s only recently gaining traction in the U.S., so many veterinary clinics don’t offer it or may not be familiar with it.


7. Can ECT replace radiation therapy?

In some cases, ECT can provide comparable local control to radiation therapy, especially for incompletely resected tumors. However, treatment decisions should be individualized based on the patient’s condition.


8. How can I find a vet offering ECT near me?

ECT is offered at a growing number of specialty and referral veterinary hospitals. Availability is increasing, but today, it is offered by a small number of clinics in any metropolitan area. For example, in the Pacific Northwest, there are only 3-4 hospitals offering ECT. Try typing “Veterinary electrochemotherapy near me” in google search. Also see if electrochemotherapy is listed as one of the services offered in your local veterinary specialty clinic's website.


Watch the Webinar

Learn how electrochemotherapy is transforming the treatment landscape for companion animals with cancer. Watch the full webinar to gain expert insights and discover whether this therapy may be appropriate for your pet.




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If you have questions, feel free to email us at info@ccralliance. We’ll respond as soon as we can!


Canine Cancer Alliance is a non-profit organization dedicated to supporting research for canine cancer cures.


All information on the Canine Cancer Alliance website is for educational purposes only. It is not intended to replace professional veterinary advice.


Always consult your veterinarian with any questions regarding your pet’s health and medical condition.

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