Lymphoma in Dogs: Latest Insights and Treatments (2025)

https://youtu.be/wHK7714Ud0E

A recorded Webinar by Dr. Kevin Choy on Canine Lymphoma, hosted by Canine Cancer Alliance, can be viewed here.

Episode Highlights

[00:02:30] 2-year lymphoma remission and how it inspired creation of nonprofit Toby’s Hope

[00:05:00] Common risk factors 

[00:10:30] Classification of lymphomas in dogs vs. humans

[00:14:00] Diagnosis and limitations of fine needle aspiration (FNA)

[00:18:00] Advanced testing: flow cytometry, PARR, and biopsy

[00:21:00] ImpriMed’s predictive lymphoma profiling and drug sensitivity testing

[00:26:00] Staging and prognostic factors (B-cell vs T-cell, substage, MDR gene)

[00:30:00] Why steroids should be delayed until diagnostics are complete

[00:34:00] Overview of CHOP chemotherapy protocol and outcomes

[00:39:00] Alternative protocols for T-cell lymphoma (LOP, MOP)

[00:43:00] New and emerging treatments: Tanovea and Laverdia

[00:48:00] Why immunotherapy and vaccines are not yet viable for canine lymphoma

[00:51:00] High-risk/high-reward treatments: stem cell transplant and radiation

[00:56:00] Clinical case: Yoki and the role of repeat ImpriMed testing

[01:01:00] Clinical case: Roger and GI T-cell lymphoma managed with LOP

[01:05:00] Clinical case: Blue and cutaneous T-cell lymphoma

[01:20:00] Financial support, pet insurance, and low-cost options

[01:24:00] Why early diagnostics and collaboration with GPs are critical

Key Quotes

“Currently we have about 30 different subtypes of lymphomas that are classified in dogs, and each of them again have their own specific diagnostic criteria, specific treatments, and prognoses.”

“CHOP is four different chemotherapy drugs... and there are essentially 16 treatments given over a 19 to 25 week protocol.”

“If we have, say, a more resistant phenotype or tougher type of lymphoma like a T cell, we really shouldn’t be treating them with CHOP. We should be using a LOP or a MOP based protocol.”

“The survival times (with half body radiation added) were over 2,000 days. So you’re talking like, you know, essentially six years.”

“A typical CHOP protocol at our hospital can sometimes range anywhere between $8,000 to $16,000 plus.”

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• Canine Cancer Causes and Prevention

• Finding better, less toxic cancer treatments for dogs with a new genomic test?

• Could This Combination Immunotherapy Help Dogs Beat Osteosarcoma (and other aggressive cancers)?

  
  

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